Xenical (Orlistat)
Purpose of Medication and Method of Action
Xenical is used to treat obesity. It acts by blocks the absorption of dietary fat from the intestine by inhibiting the intestinal enzyme lipase. Lipase is responsible for breaking down dietary fat to forms that can be absorbed into the body. After one year of Xenical and a reduced-calorie diet the average weight loss was 13 lbs.
Side Effects
Among the more common side effects are due to the increasec amount of non-absorbed lipids passing through the intestine and include: gas with discharge, oily stools, and an increased number of bowel movements.
Drug Interactions
Xenical will reduce the absorption of fat soluble vitamins although no reports of vitamin deficiency symptoms have occurred. The blood levels of the 3statin2 group of drugs used to reduce cholesterol may occur - the clinical significance of this is unknown. Vitamin K levels, important in the response to Coumadin (warfarin) may decrease and increased attention to coagulation parameters should occur while on both drugs.
Cautions and Contraindications
Xenical is not to be used in patients with malabsorption syndromes or those with impaired gall bladder function.
Usual Dose
One capsule (120 mg) with every fat containing meal.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.