Trazadone
Purpose of Medication and Method of Action
Trazadone is an antidepressant which may act by preventing the reuptake of serotonin into neurons. Thus, it potentiates the action of 5-hydroxytryptamine, the precusor of serotonin.
Side Effects
The most common side effects are: drowsiness (24%), dizziness (20%), tiredness (11%), dry mouth (14%), nervousness (15%), nausea, headache, and insomnia (10%).
Drug Interactions
There is limited evidence that trazadone may increase serum digoxin or phenytoin levels. Trazadone may alter the response to warfarin (Coumadin) and careful following of blood anticoagulant activity is urged if trazadone is added to existing warfarin therapy.
Cautions and Contraindications
Trazadone may produce priapism. Should inappropriate erections occur in a man taking trazadone, call your physician immediately.
Usual Dose
An initial dose of 150 mg/day in divided doses increasing to a maximum of 400 mg/day.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.