Quinine
Purpose of Medication and Method of Action
Quinine has been used historically as one of the treatments for malaria. In addition, it has proven useful for the treatment of leg cramps, especially those occurring at night. The mechanism of action is not known.
Side Effects
The most common include: diarrhea, rash, flushing of the skin and dizziness. Rarely, blood disorders, fever, confusion, and apprehension may occur. Also reported are a variety of vision problems including blurring, photophobia and diplopia.
Drug Interactions
Quinine may increase blood levels of digoxin and when used together, blood levels of digoxin should be followed closely. Quinine can increase the anticoagulant activity of warfarin and the two should be used together with great caution.
Cautions and Contraindications
Hypersensitivity (allergic) reactions are common. Avoid in those with any history of an allergy to quinine or quinidine.
Usual Dose
Malaria: 2 capsules three times a day. Leg cramps – once daily.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.