Prozac (Fluoxetine)
Purpose of Medication and Method of Action
Prozac is used to treat depression, obsessive-compulsive disorders, and bulemia. It most likely works by preventing the uptake of serotonin into the brain thus allowing for the accumulation of serotonin in the brain responsible for regulating mood.
Side Effects
The most common side effects are: insomnia, nervousness, drowsiness, and dizziness. Also reported are: excessive sweating, and tremor. Weight gain due to increased appetite may also occur. Patients, especially men, may experience a decrease in libido.
Drug Interactions
Prozac may increase blood levels of anticonvulsants and require a lower dose of the anticonvulsant to avoid side effects. Similarly, there is evidence that Prozac can increase the activity of minor tranquilizers in the benzodiazepine class such as lorazepam and alprazolam as well as tricyclic antidepressants such as amitriptyline. Prozac may temporarily increase blood levels of the anticoagulant, warfarin, and careful monitoring of coagulation parameters should be conducted during the first few months of Prozac therapy.
Cautions and Contraindications
Patients taking monoamine oxidase inhibitors (MAOI’s) should NOT take Prozac at the same time. Wait at least 14 days between stopping a MAOI drug before starting Prozac and five weeks after stopping Prozac before starting a MAOI.
Usual Dose
The usual dose is 20-80 mg/day with 20 mg as the recommended starting dose. It may take up to 1-2 months to realize the full benefits of this medication.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.