Protopic (Tacrolimus) Ointment
Purpose of Medication and Method of Action
Protopic ointment is used for the treatment of eczema (atopic dermitis). Although its mechanism of action is unknown, when tacrolimus is given by mouth it suppresses the immune system. Thus, the action when applied to the skin may be to prevent the inflammatory response associated with eczema. Over 70% of patients experience a greater than 50% improvement in symptoms after using the ointment for 12 weeks.
Side Effects
The most common side effect is skin burning (approx. 30%), followed by itching (approx. 25%) and flu-lid symptoms (approx. 15%). The incidence of these side effects is somewhat higher in children than in adults. These side effects lessen with continues use of the ointment.
Drug Interactions
None reported
Cautions and Contraindications
Because this drug may increase the carcinogenic potential of the ultraviolet rays from sunlight, the area where the ointment has been applied should be protected from direct exposure to the sun.
Usual Dose
Protopic is usually applied two times a day as a thin layer. Run in skin until none remains. Do not use with occlusive dressing.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.