Premarin (Conjugated Estrogens)

Purpose of Medication and Method of Action

Premarin is an estrogen and is indicated for the treatment of moderate to severe vasomotor symptoms flushing, hot flashes) associated with menopause, vaginal or vulvar atrophy, and prevention of osteoporosis.

Side Effects

The most common side effects are: nausea, vomiting, abdominal cramps, change in menstrual flow, breast tenderness, edema, and a change in pigmentation (which may persist). The most significant and potentially dangerous side effect is the formation of blood clots which can lead to thrombophlebitis (vein inflammation) and rarely, pulmonary emboli (blood clots which lodge in the lung). Should you notice pains in your legs or chest pains contact your physician immediately!!

Drug Interactions

None

Cautions and Contraindications

A history of clotting disorders or thrombophlebitis.

Usual Dose

One tablet each day.

Patient Medication Information

These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.