Oxybutynin (Dithropan)
Purpose of Medication and Method of Action
Oxybutynin is an antispasmotic drug which produces relaxation of the bladder. Thus, it decreases urgency and the frequency of both incontinent episodes and voluntary urination., The mechanism of action is to inhibit the effect of acetylcholine on the bladder muscle thus producing bladder relaxation.
Side Effects
Dry mouth (60%), constipation (13%), sleepiness (12%), and headache (10%).
Drug Interactions
Do not use with any other medications which also have anticholinergic effects: those include antihistamines such as diphenhydramine (Benadryl) and tricyclic antidepressants such as amitriptyline (Elavil) and imipramine (Tofranil).
Cautions and Contraindications
Do not use in presence of bladder outflow onstruction or narrow angle glaucoma.
Usual Dose
The usual dose is 10-30 mg/day in divided doses.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.
