Lisinopril (Prinivil)
Purpose of Medication and Method of Action
Lisinopril is used to treat high blood pressure. It inhibits the action of angiotensin converting enzyme (ACE). This inhibition reduces blood pressure by preventing the formation of Angiotensin II, a biochemical produced by the kidney which increases blood sodium (greater water retention). It is usually used along with other drugs for high blood pressure.
Side Effects
The most common side effects are: dizziness, a persistent cough, fatigue, and nausea. Should the cough become troublesome, contact your physician. Rarely, a condition called angioedema characterized by swelling of the face and hands may occur - if so, call your physician immediately.
Drug Interactions
If used with potassium sparing diuretics such as triamterene, an increase in blood potassium may result with an adverse effect on the heart. Vasotec may reduce the absorption of the antibiotic tetracycline. The blood level of lithium may be increased by Vasotec and extreme caution should be exercised when Accupril is added to existing lithium therapy.
Cautions and Contraindications
The dose needs to be modified downward if kidney function is impaired. This drug should not be used in second and third trimester of pregnancy.
Usual Dose
Initially, 5 mg each day to a maximum of 20-40 mg daily in two divided doses. You should take (or have) your blood pressure taken once weekly and record the value and take with you on next visit to your physician.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.