Diclofenac (Voltaren R)
Purpose of Medication and Method of Action
Diclofenac is a non-steroidal antiinflammatory drug (NSAID). It is indicated for the treatment of a variety of inflammatory conditions including: arthritis (osteo- and rheumatoid), muscle strains, bursitis, and as a general analgesic drug. Its antiinflammatory activity may be due to its ability to interfere with the production of prostaglandins, one of the biochemicals in the body which may be responsible for inflammation.
Side Effects
The most significant and dangerous side effect is gastrointestinal bleeding thus this drug must be taken with meals to reduce this possibility. A dark stool is a indicator that this drug must be stopped immediately and your physician called. Other side effects which may be more common but less significant include: nausea, skin rashes, heartburn, tinnitus (ringing in ears) and dizziness. When first taking this drug, exercise caution when driving until you know if you are going to develop any of those symptoms.
Drug Interactions
DO NOT TAKE ANY ASPIRIN, IBUPROFEN, NAPROXEN OR ANY OTHER NON-STEROIDAL DRUGS TO TREAT ARTHRITIS WHILE TAKING DICLOFENAC. Diclofenac may reduce the effectiveness of diuretics such as furosemide (Lasix). It may also increase the activity of methotrexate and the two drugs should not be used together except under the supervision of your physician.
Cautions and Contraindications
Avoid diclofenac in patients with a history of gastrointestinal bleeding.
Usual Dose
The usual dose is 100-150 mg a day taken with meals.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.