Diazoxide

Purpose of Medication and Method of Action

Diazoxide is a nondiuretic thiazide-like compound which is taken orally for the treatment of hypoglycemia.

Side Effects

The most significant side effect is fluid retention which does respond to diuretic therapy. Ketoacidosis and hyperosmolar coma have been rarely reported.

Drug Interactions

Use of thiazide diuretics with diazoxide can significantly increase the hyperglycemic effects of diazoxide.

Cautions and Contraindications

None

Usual Dose

The usual dose is 1 mg/kg three times a day with an average adult dose of 200 mg/day in three divided doses. To make a suspoension for oral administration. Place 5 Gm (5000 mg) diazoxide powder in 100 ml of chocolate milk to create a suspension of 50 mg/ml. SHAKE WELL!! Use a 3 ml syringe to administer correct dose orally. DO NOT INJECT!!

Note

Protect from light.

Patient Medication Information

These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.