Clomiphene

Purpose of Medication and Method of Action

Clomiphene is indicated in the treatment of ovulatory dysfunction in women who desire pregnancy. It acts by initiating a series of endocrine events culminating in preovulatory gonadotropin surge and subsequent follicular rupture with release of ova.

Side Effects

Side effects include ovarian enlargement (14%), hot flushes (10%), abdominal discomfort (6%), nausea (2%) and breast discomfort (2%).

Drug Interactions

None reported

Cautions and Contraindications

Pregnancy, liver disease, and presence of cystic ovaries

Usual Dose

One tablet (50mg) for 5 days.

Patient Medication Information

These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.