Benicar and Benicar HCT (Olmesartan with or without Hydrochloethiazide)

Purpose of Medication and Method of Action

Benicar and Benicar HCT are indicated for the treatment of hypertension. Benicar itself acts to prevent the formation of angiotensin II, a vasoconstrictor produced in the body. Hydrochlorthiazide (HCTZ) promotes the excretion of sodium and with it, excess water. The net result is a reduction of blood volume and a subsequent reduction of blood pressure.

Side Effects

The most common side effects are dizziness (9%), upper respiratory tract infections (7%), and nausea (3%).

Drug Interactions

There are no known interactions with olmesartan. Non-steroidal anti inflammatory drugs may decrease the effectiveness of HCTZ. Patients taking HCTZ should not be given lithium.

Cautions and Contraindications

Diuretics of the class to which HCTZ belongs may cause blood electrolyte abnormalities thus intermittent blood testing for such changes is recommended. Occasionally HCTZ may increase blood glucose levels.

Usual Dose

Olmesartan 20-40 mg each day.

Patient Medication Information

These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.