Arava (Leflunomide)

Purpose of Medication and Method of Action

Arava is a drug which inhibits a step in the inflammation process. It is approved for use in the treatment of rheumatoid arthritis.

Side Effects

The most common side effects are: diarrhea, headache, and a rash. Alopecia (loss of hair) has occurred in 10% of patients taking Arava. An increase in liver enzymes may occur thus monitoring of liver enzymes for the first few months of therapy is suggested.

Drug Interactions

Use with caution in other drugs known to affect liver function e.g. methotrexate. Use with rifampoin may result in increased Arava blood levels and toxicity.

Cautions and Contraindications

Women of childbearing age who are considering pregnancy.

Usual Dose

One tablet each day.

Patient Medication Information

These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.