Altace (Ramipril)

Purpose of Medication and Method of Action

Altace is used to treat high blood pressure. It inhibits the action of angiotensin converting enzyme (ACE). This inhibition reduces blood pressure by preventing the formation of Angiotensin II, a biochemical produced by the kidney which increases blood sodium (greater water retention). It is usually used along with other drugs for high blood pressure.

Side Effects

The most common side effects are: dizziness, a persistant cough, fatigue, and nausea. Should the cough become troublesome, contact your physician. Rarely, a condition called angioedema characterized by swelling of the face and hands may occur - if so, call your physician immediately.

Drug Interactions

If used with potassium sparing diuretics such as triamterene, an increase in blood potassium may result with an adverse effect on the heart. Altace may reduce the absorption of the antibiotic tetracycline. The blood level of lithium may be increased by Altace and extreme caution should be exercised when Accupril is added to existing lithium therapy.

Cautions and Contraindications

The dose needs to be modified downward if kidney function is impaired.

Usual Dose

Initially, 2.5 mg twice daily increasing to a maintenance does of 5 mg twice daily.

Patient Medication Information

These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.