Agrylin (Anagrelide)
Purpose of Medication and Method of Action
Agrylin is used to reduce total platelet count. Thus, it is used to treat primary essential thrombocythemia, a condition where there are too many platelets. The symptoms of this condition, headache, dizziness, and visual symptoms are significantly improved with this drug. The mechanism of action is unknown.
Side Effects
The most common side effects are: headache, diarrhea, weakness, edema (accumulation of fluid in ankles and legs), irregular heart rate and abdominal pain. The incidence of side effects increases with increasing dose.
Drug Interactions
None reported.
Cautions and Contraindications
None
Usual Dose
Starting dose - 0.5 mg four times a day. Maintenance - adjusted based on platelet count usually 1.5 to 3.0 mg a day in divided doses - not to exceed 10 mg/day.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company.