Aciphex (Rabeprazole)
Purpose of Medication and Method of Action
Aciphex is used to treat the symptoms of acid reflux (heartburn). Continued acid reflux into the esophagus can result in erosion of the esophagus and chronic damage. Aciphex acts by inhibiting the secretion of hydrochloric acid (HCl) into the stomach (proton pump inhibitor) thus decreasing acidity and making the stomach contents less irritating to the esophagus. It is useful in treating duodenal ulcers which may also be aggravated by HCl produced in the stomach. It is also approved for use in Zollinger-Ellison syndrome excess production of HCl in the stomach.
Side Effects
Rare with only headache being the only common side effect experienced at a rate greater than placebo. Many other side effects have been reported but the incidence is less than 1 in 1000 patients. As with any drug should you notice anything unusual, tiredness, easy bruising, abdominal pain you should contact your physician to be sure it may not be related to Aciphex.
Drug Interactions
Aciphex may reduce the blood levels of the antifungal drug, ketokonazole requiring an increase in ketokonazole dose.
Usual Dose
One tablet (20 mg) taken daily. The tablets should not be crushed or broken.
Patient Medication Information
These information sheets do not list all known side effects of the medications, only the most common side effects. For a complete list of side effects please contact your local pharmacy or the actual drug manufacturing company